933 East Main in 1919 housed Parker's Drug Store, run by Roland H. Parker. By 1923, it housed the Edgemont Candy Kitchen, run by either "GL Orthanos" or "Augustus L Orphanos", depending upon which page of the city directory you believe; he lived at 520 1/2 East Pettigrew St.
1933: Reeves Square Deal Cafe
1937: Lipscomb Bros. Barbers
1944: Lipscomb Bros. Barbers
1960: Kale Drug Co.
By the early 1990s, it served as offices for the Hayti Development Corporation, which I wrote a bit about here.
931-933 East Main, 03.28.03
In one of those try-devine-what-is-happening-from-the-tax-records, the building is now owned by DRJR Properties, i.e. John Runge and Darius Robustelli, who own "Carmine's Ristorane & Pizzeria" in Chapel Hill. They leased it in 2008 to Daniel Sams and Keith Yokley, for a total term of 5 years.
Nothing outwardly appears to be happening with the building.
Find this spot on a Google Map.